Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 19/20 | 0.57 |
| ▸ | BACE2 | Q9Y5Z0 | 6/20 | 0.57 |
| ▸ | CTSD | P07339 | 2/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339052 | 0.79 | BACE1 (0.58) | BACE1BACE2CTSDAPP | |
| SCHEMBL7880652 | 0.76 | BACE1 (0.62) | BACE1BACE2CTSDAPP | |
| SCHEMBL7866943 | 0.76 | BACE1 (0.50) | BACE1BACE2CTSD | |
| SCHEMBL8338864 | 0.73 | BACE1 (0.46) | BACE1BACE2CTSDAPP | |
| SCHEMBL4216477 | 0.73 | BACE1 (0.84) | BACE1BACE2CTSDAPPCYP3A4 | |
| SCHEMBL20899826 | 0.73 | BACE1 (1.00) | BACE1BACE2CTSDAPP | |
| SCHEMBL29470573 | 0.73 | BACE1 (1.00) | BACE1BACE2CTSDAPP | |
| SCHEMBL21527047 | 0.73 | BACE1 (1.00) | BACE1BACE2CTSDAPP | |
| SCHEMBL4567212 | 0.73 | BACE1 (1.00) | BACE1BACE2CTSDAPP | |
| SCHEMBL8341359 | 0.73 | BACE1 (0.45) | BACE1BACE2CTSDAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |