Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920132 | 0.94 | CCKBR (0.91) | CCKBR | |
| SCHEMBL8402158 | 0.93 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8920129 | 0.91 | CCKBR (0.87) | CCKBR | |
| SCHEMBL8920927 | 0.91 | CCKBR (1.00) | CCKBR | |
| SCHEMBL7874140 | 0.91 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8920529 | 0.89 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8404668 | 0.89 | CCKBR (0.80) | CCKBR | |
| SCHEMBL8920089 | 0.88 | CCKBR (0.89) | CCKBR | |
| SCHEMBL8924370 | 0.88 | CCKBR (0.85) | CCKBR | |
| SCHEMBL8922090 | 0.88 | CCKBR (0.90) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319915-B1 | ADMINISTERING BENZAZEPIENE DERIVATIVE TO MAMMAL FOR THERAPY OF CANCER | PFIZER INC. | 2001-11-20 | — | — | US | claimed |
| US-6319915-B1 | ADMINISTERING BENZAZEPIENE DERIVATIVE TO MAMMAL FOR THERAPY OF CANCER | PFIZER INC. | 2001-11-20 | — | — | US | disclosed |
| EP-0711283-B1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5618811-A | Tetrahydro-1H-benzazepinones and hexahydroazepinones as selective cholecystokinin-B receptor antagonists | PFIZER INC. (US) | 1997-04-08 | — | — | US | disclosed |