SCHEMBL7874223

SCHEMBL7874223

CC1(C)CC=C(c2ccc(OCc3ccccc3)cc2)c2cc(C=Cc3ccc(C(=O)O)cc3)ccc21

nearest known ligand 0.74

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RARA P10276 17/20 0.74
RARB P10826 17/20 0.74
RARG P13631 16/20 0.74
RXRA P19793 1/20 0.74
NR2E1 Q9Y466 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7874221 1.00 RARA (0.74) RARARARBRARGRXRANR2E1
SCHEMBL7811795 0.92 RARA (0.62) RARARARBRARGRXRANR2E1
SCHEMBL7874215 0.87 RARB (0.57) RARARARBRARGRXRANR2E1
SCHEMBL29613352 0.86 RARA (1.00) RARARARBRARGRXRANR2E1
SCHEMBL6755033 0.86 RARA (1.00) RARARARBRARGRXRANR2E1
SCHEMBL6755036 0.86 RARA (1.00) RARARARBRARGRXRANR2E1
SCHEMBL30561847 0.85 RARA (0.78) RARARARBRARGRXRANR2E1
SCHEMBL6754156 0.85 RARA (0.78) RARARARBRARGRXRANR2E1
SCHEMBL6754150 0.85 RARA (0.78) RARARARBRARGRXRANR2E1
SCHEMBL6754897 0.82 RARA (0.80) RARARARBRARGRXRANR2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6319948-B2 PREVENTION AND/OR MINIMIZATION OF SURGICAL ADHESION FORMATION BY ADMINISTERING CERTAIN SUBSTITUTED (5,6)-DIHYDRONAPHTHALENYL COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY 2001-11-20 US disclosed