Acetic Acid

Acetic Acid

SCHEMBL7874644

CC(=O)[O-].CCOc1ccccc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.46
MAPT P10636 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
GLA P06280 1/20 0.46
KDM4E B2RXH2 3/20 0.43
ATM Q13315 2/20 0.43
POLB P06746 1/20 0.43
GAA P10253 2/20 0.42
CYP2C19 P33261 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.41
ALOX15 P16050 1/20 0.41
HTT P42858 1/20 0.41
ALDH1A1 P00352 3/20 0.40
HTR7 P34969 1/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 2/20 0.40
CACNA1F O60840 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CACNA1D Q01668 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL7874754 0.91 MRGPRX4 (0.44) L3MBTL1MAPTNPSR1GLAKDM4E
Bromide SCHEMBL4183772 0.88 L3MBTL1 (0.50) L3MBTL1MAPTNPSR1GLAKDM4E
Hydrochloric Acid SCHEMBL7874554 0.88 L3MBTL1 (0.50) L3MBTL1MAPTNPSR1GLAKDM4E
Water SCHEMBL4390658 0.88 L3MBTL1 (0.50) L3MBTL1MAPTNPSR1GLAKDM4E
Phenol SCHEMBL7877220 0.85 L3MBTL1 (0.45) L3MBTL1MAPTNPSR1GLAKDM4E
SCHEMBL4383103 0.81 L3MBTL1 (0.44) L3MBTL1MAPTNPSR1GLAKDM4E
Acetic Acid SCHEMBL7874650 0.80 MRGPRX4 (0.44) L3MBTL1MAPTGLAKDM4EPOLB
Bromide SCHEMBL11008766 0.77 ELANE (0.42) L3MBTL1MAPTGLAKDM4ECYP2C19
Bromide SCHEMBL4171091 0.76 SLC6A2 (0.47) L3MBTL1MAPTNPSR1ATMCYP2C19
Bromide SCHEMBL3593928 0.75 CYP1A2 (0.47) L3MBTL1MAPTNPSR1ATMCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316575-B1 MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed