SCHEMBL7874916

SCHEMBL7874916

CCCCCn1cnc2cc(OC)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.55
GAA P10253 2/20 0.55
KDM4E B2RXH2 4/20 0.53
HSD17B10 Q99714 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
ALDH1A1 P00352 2/20 0.53
ALOX15 P16050 1/20 0.53
LMNA P02545 3/20 0.52
NR1I2 O75469 2/20 0.50
FGFR1 P11362 3/20 0.49
HPGD P15428 3/20 0.48
TDP1 Q9NUW8 1/20 0.48
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
HTT P42858 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19848227 0.96 MAPT (0.58) MAPTGAAKDM4EHSD17B10SMN1; SMN2
SCHEMBL19848077 0.90 MAPT (0.65) MAPTGAAKDM4EHSD17B10SMN1; SMN2
SCHEMBL22135376 0.87 MAPT (0.52) MAPTGAAKDM4EHSD17B10SMN1; SMN2
SCHEMBL9041325 0.87 MAPT (0.51) MAPTGAAKDM4EHSD17B10SMN1; SMN2
SCHEMBL19911348 0.86 KDM4E (0.50) MAPTGAAKDM4EHSD17B10SMN1; SMN2
SCHEMBL19911358 0.84 MTNR1A (0.61) MAPTGAAKDM4EHSD17B10SMN1; SMN2
SCHEMBL6758619 0.83 NPC1 (0.65) MAPTGAAKDM4EHSD17B10SMN1; SMN2
SCHEMBL6638182 0.82 MTNR1A (0.52) MAPTGAAKDM4EHSD17B10SMN1; SMN2
SCHEMBL19911350 0.82 MAPT (0.44) MAPTGAAKDM4EHSD17B10SMN1; SMN2
SCHEMBL5332534 0.81 MAPT (0.44) MAPTGAAKDM4EHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132566-A1 STING PYRAZOLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 WO disclosed
US-6329135-B1 LIGHT INSENSITIVE ORGANIC SILVER SALT ON A SUPPORT KONICA CORPORATION (JP) 2001-12-11 US disclosed
EP-1058151-A1 Silver halide photothermographic material KONICA CORPORATION (JP) 2000-12-06 EP disclosed
EP-0562476-B1 Method for preparing a silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 2000-10-04 EP disclosed
EP-0772088-B1 Heat-developable diffusion transfer color photographic material FUJI PHOTO FILM CO LTD (JP) 2000-09-13 EP disclosed
EP-0625726-B1 Methine compound and silver halide photographic material comprising the same FUJI PHOTO FILM CO LTD (JP) 2000-08-09 EP disclosed
US-6068968-A CYANINE DYE HAVING AT LEAST ONE SUBSTITUENT HAVING A THIOETHER GROUP; EXHIBITING LOW FOGGING, HIGH SENSITIVITY, AND IMPROVED STORAGE STABILITY. FUJI PHOTO FILM CO., LTD. (JP) 2000-05-30 US disclosed
EP-0638841-B1 Methine compounds and silver halide photographic materials containing the compound FUJI PHOTO FILM CO LTD (JP) 2000-04-19 EP disclosed
US-6027870-A INFRARED-SENSITIVE PHOTOTHERMOGRAPHIC MATERIAL CONTAINING A CYANINE DYE; STORAGE STABILITY, ANTIFOGGING AGENTS FUJI PHOTO FILM CO., LTD. (JP) 2000-02-22 US disclosed
EP-0647878-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 2000-01-12 EP disclosed
EP-0047470-B1 METHOD FOR IMMUNOCHEMICAL MEASUREMENT FUJI PHOTO FILM CO., LTD. (JP) 1985-04-24 EP disclosed
US-4473652-A LABELLING WITH CYANINE OR MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1984-09-25 US disclosed
US-4414325-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1983-11-08 US disclosed
EP-0048834-A1 Method for measurement of trace enzymes FUJI PHOTO FILM CO., LTD. (JP) 1982-04-07 EP disclosed
EP-0047470-A1 Method for immunochemical measurement FUJI PHOTO FILM CO., LTD. (JP) 1982-03-17 EP disclosed
US-4225666-A Silver halide precipitation and methine dye spectral sensitization process and products thereof EASTMAN KODAK COMPANY (US) 1980-09-30 US disclosed
US-4199360-A DISSOLVING METHINE DYE IN PRESENCE OF RED SHIFT COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-04-22 US disclosed
US-4183756-A PRECIPITATION OF WILVER HALIDE PARTICLES IN PRESENCE OF METHINE DYE EASTMAN KODAK COMPANY (US) 1980-01-15 US disclosed
US-4138266-A SULFO-SUBSTITUTED CYANINE AND RED SHIFT TRIAZOLE DYES FUJI PHOTO FILM CO., LTD. (JP) 1979-02-06 US disclosed
US-3955996-A Method for spectrally sensitizing photographic light-sensitive emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US disclosed