SCHEMBL7875124

SCHEMBL7875124

Nc1c(F)c(F)c(F)c(Oc2c(F)c(N)c(F)c(F)c2F)c1F

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
POLB P06746 1/20 0.35
HSP90AA1 P07900 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12929083 0.97 MAPT (0.38) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL30688717 0.94 MAPT (0.39) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL4805284 0.94 MAPT (0.39) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL6003462 0.94 MAPT (0.42) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL722867 0.94 MAPT (0.42) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL5404508 0.88 MAPT (0.39) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL1334193 0.86 MAPT (0.38) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL2128818 0.86 MAPT (0.38) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL26037420 0.81 MAPT (0.35) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL3623855 0.81 MAPT (0.35) MAPTKDM4ECRHBPCRHR2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110003118-A1 MEMBER FOR IMAGE FORMING APPARATUS, IMAGE FORMING APPARATUS, AND UNIT FOR IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2011-01-06 US disclosed
US-20110003118-A1 MEMBER FOR IMAGE FORMING APPARATUS, IMAGE FORMING APPARATUS, AND UNIT FOR IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2011-01-06 US disclosed
US-6303743-B1 Polyimide for optical communications, method of preparing the same, and method of forming multiple polyimide film using the polyimide SAMSUNG ELECTRONICS CO., LTD. (KR) 2001-10-16 US disclosed
US-6115514-A FILM THICKNESS OF POLYIMIDE FILM FORMED BY THERMALLY IMIDIZING A POLYAMIC ACID IS SET AT NOT MORE THAN 20 MICROMETERS; HUMIDITY RESISTANCE, STRENGTH, FLEXIBILITY NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 2000-09-05 US disclosed
US-6100371-A Polyimide for optical communications and method for preparing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-08-08 US disclosed
US-6077928-A Bis(dialkylmaleimide) derivative and polyetherimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-06-20 US disclosed
US-6072920-A Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 2000-06-06 US disclosed
US-6048986-A DEHYDRATION OF DIFLUOROPYROMELLITIC ACID TO FORM DIFLUOROPYROMELLITIC DIANHYDRIDE NIPPON TELEGRAPH AND TELEPHONE CORP. (JP) 2000-04-11 US disclosed
US-6028159-A Polyamideimide for optical communications and method for preparing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-02-22 US disclosed
US-6013759-A Polyamideimide for optical communications and method for preparing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-01-11 US disclosed
EP-0623830-B1 Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH & TELEPHONE (JP) 1999-08-18 EP disclosed
US-5901259-A Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1999-05-04 US disclosed
US-5849934-A Method for preparing aromatic compounds NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1998-12-15 US disclosed
US-5750731-A POLYIMIDE ANHYDRIDE MONOMERS NIPPON TELEGRAPH & TELEPHONE CORPORATION (JP) 1998-05-12 US disclosed
US-5694496-A WAVEGUIDE COMPRISING AN AROMATIC FLUORO-POLYIMIDE; HEAT RESISTANCE, FLEXIBILITY, WATERPROOFING, STRENGTH NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1997-12-02 US disclosed
EP-0480266-B1 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH & TELEPHONE (JP) 1996-06-26 EP disclosed
US-5449741-A Electronics with impact strength NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1995-09-12 US disclosed
EP-0623830-A1 Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1994-11-09 EP disclosed
US-5233018-A Heat resistance and low optical transmission loss in the near-infrared region; integrated circuits NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1993-08-03 US disclosed
EP-0480266-A2 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-15 EP disclosed