SCHEMBL722867

SCHEMBL722867

Nc1c(F)c(F)c(Oc2c(F)c(F)c(N)c(F)c2F)c(F)c1F

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
POLB P06746 1/20 0.38
HSP90AA1 P07900 1/20 0.38
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 1/20 0.32
CA12 O43570 1/20 0.30
CA7 P43166 1/20 0.30
CA13 Q8N1Q1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6003462 1.00 MAPT (0.42) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL7875124 0.94 MAPT (0.39) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL4805284 0.94 MAPT (0.39) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL2128818 0.91 MAPT (0.38) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL1334193 0.91 MAPT (0.38) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL5404508 0.88 MAPT (0.39) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL7552402 0.81 MAPT (0.35) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL4750265 0.81 MAPT (0.35) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL3623855 0.81 MAPT (0.35) MAPTKDM4ECRHBPCRHR2POLB
SCHEMBL2001423 0.78 CA1 (0.38) MAPTKDM4ECRHBPCRHR2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591535-B Recovery method of nano-cluster crosslinked organic-inorganic hybrid crosslinked polymer 北京化工大学 2022-12-09 CN claimed
US-20220177650-A1 POLYIMIDE FILM PREPARATION METHOD AND APPLICATION THEREOF INSTITUTE OF CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2022-06-09 US claimed
CN-111100596-B Fluorine-containing polyimide binder, flexible metal laminated plate and preparation method thereof 东莞东阳光科研发有限公司 2021-11-12 CN claimed
WO-2020200229-A1 POLYIMIDE THIN FILM AND PREPARATION METHOD AND APPLICATION THEREOF 中国科学院化学研究所 2020-10-08 WO claimed
US-9034423-B2 Method of making a fuser member XEROX CORPORATION (US) 2015-05-19 US claimed
US-20140178579-A1 METHOD OF MAKING A FUSER MEMBER XEROX CORPORATION (US) 2014-06-26 US claimed
US-20140171588-A1 COMPOSITION FOR FLEXIBLE SUBSTRATE AND FLEXIBLE SUBSTRATE FORMED FROM THE SAME CHI MEI CORPORATION (TW) 2014-06-19 US claimed
CN-103865264-A COMPOSITION FOR FLEXIBLE SUBSTRATE AND FLEXIBLE SUBSTRATE CHI MEI CORP 2014-06-18 CN claimed
US-20120049123-A1 PHOSPHATE ESTER POLYIMIDE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2012-03-01 US claimed
US-8029901-B2 Polyaryl ether copolymer containing intermediate transfer members XEROX CORPORATION (US) 2011-10-04 US claimed
US-20100279214-A1 POLYARYL ETHER COPOLYMER CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2010-11-04 US claimed
US-6397034-B1 CONTROLLING CONDUCTIVITY XEROX CORPORATION 2002-05-28 US claimed
US-6066400-A Polyimide biasable components XEROX CORPORATION (US) 2000-05-23 US claimed
US-6013759-A Polyamideimide for optical communications and method for preparing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-01-11 US claimed
US-20260071028-A1 BINDER FOR ENERGY STORAGE DEVICE, ELECTRODE FOR ENERGY STORAGE DEVICE, ENERGY STORAGE DEVICE, POLYMER COMPOSITE, AND PRODUCTION METHOD OF BINDER FOR ENERGY STORAGE DEVICE UBE CORP (JP) 2026-03-12 US disclosed
US-12548768-B2 Active material layer for negative electrode, method for producing same, electrode mixture paste for power storage device negative electrode, negative electrode for power storage device, and power storage device UBE CORPORATION (JP) 2026-02-10 US disclosed
EP-4674891-A1 POLYIMIDE POWDER FOR MOLDED BODY, AND POLYIMIDE MOLDED BODY UBE Corporation (JP) 2026-01-07 EP disclosed
EP-0179604-A2 Polyimide adhesives, coats and prepreg MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-04-30 EP disclosed
US-4271288-A TETRACARBOXYLIC ACID BONDED TO ARYLENE MOIETY VIA METHYLENE GROUPS THE DOW CHEMICAL COMPANY (US) 1981-06-02 US disclosed
US-4124651-A Process for the production of polyamide-polyamide-acid copolymers CIBA-GEIGY CORPORATION (US) 1978-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12548768-B2 Active material layer for negative electrode, method for producing same, electrode mixture paste for power storage device negative electrode, negative electrode for power storage device, and power storage device ORAI1, ASIC1, TMCO1 MAPT 326/4885KDM4E 684/4885CRHBP 1529/4885
US-20260071028-A1 BINDER FOR ENERGY STORAGE DEVICE, ELECTRODE FOR ENERGY STORAGE DEVICE, ENERGY STORAGE DEVICE, POLYMER COMPOSITE, AND PRODUCTION METHOD OF BINDER FOR ENERGY STORAGE DEVICE TBCA, TBCD, TBCB MAPT 76/4885KDM4E 427/4885CRHBP 808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.