Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.43 |
| ▸ | MGAM | O43451 | 5/20 | 0.43 |
| ▸ | SI | P14410 | 5/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935212 | 0.73 | CYP1A2 (0.50) | CYP1A2CA9CA12CYP1B1CYP1A1 | |
| SCHEMBL6629828 | 0.73 | CYP1A2 (0.47) | MCL1CYP1A2CA9CA12CYP3A4 | |
| SCHEMBL29384225 | 0.70 | TRPM4 (0.43) | ALDH1A1CYP1A2CA9HPGDKDM4E | |
| SCHEMBL4536799 | 0.68 | CYP2B6 (0.47) | GAAALDH1A1CYP1A2HPGDKDM4E | |
| SCHEMBL18172254 | 0.66 | GAA (0.81) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7784100 | 0.65 | CYP1A2 (0.40) | ALDH1A1CYP1A2CA9HPGDKDM4E | |
| SCHEMBL1860857 | 0.64 | ALDH1A1 (0.72) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL29859562 | 0.64 | ALDH1A1 (0.72) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL450134 | 0.62 | CA12 (0.60) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL27886615 | 0.62 | ALDH1A1 (0.58) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313320-B1 | DESULFONATION, DEBLOCKING, DEPROTECTING; VIRICIDES | CHIROTECH TECHNOLOGY, INC. (GB) | 2001-11-06 | — | — | US | claimed |
| WO-2000064902-A2 | PROCESS FOR THE PREPARATION OF CALANOLIDE PRECURSORS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | claimed |
| US-6313320-B1 | DESULFONATION, DEBLOCKING, DEPROTECTING; VIRICIDES | CHIROTECH TECHNOLOGY, INC. (GB) | 2001-11-06 | — | — | US | disclosed |
| WO-2000064902-A2 | PROCESS FOR THE PREPARATION OF CALANOLIDE PRECURSORS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |