Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875505 | 1.00 | MGAM (0.39) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL14775508 | 0.87 | ALDH1A1 (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2149292 | 0.77 | — | — | |
| SCHEMBL3240184 | 0.77 | — | — | |
| SCHEMBL14260247 | 0.77 | — | — | |
| SCHEMBL6968817 | 0.76 | — | — | |
| SCHEMBL6968821 | 0.76 | — | — | |
| SCHEMBL9540437 | 0.75 | — | — | |
| SCHEMBL5932376 | 0.75 | — | — | |
| SCHEMBL5932372 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313320-B1 | DESULFONATION, DEBLOCKING, DEPROTECTING; VIRICIDES | CHIROTECH TECHNOLOGY, INC. (GB) | 2001-11-06 | — | — | US | claimed |
| US-6313320-B1 | DESULFONATION, DEBLOCKING, DEPROTECTING; VIRICIDES | CHIROTECH TECHNOLOGY, INC. (GB) | 2001-11-06 | — | — | US | disclosed |
| WO-2000064902-A2 | PROCESS FOR THE PREPARATION OF CALANOLIDE PRECURSORS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |