Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876015 | 1.00 | HPGD (0.53) | HPGDMEN1KMT2ATHRBMAPT | |
| SCHEMBL7871329 | 0.87 | HPGD (0.53) | HPGDMEN1KMT2ATHRBMAPT | |
| SCHEMBL7871328 | 0.87 | HPGD (0.53) | HPGDMEN1KMT2ATHRBMAPT | |
| SCHEMBL7871316 | 0.82 | ALDH1A1 (0.39) | HPGDMEN1KMT2ATHRBMAPT | |
| SCHEMBL7871317 | 0.82 | ALDH1A1 (0.39) | HPGDMEN1KMT2ATHRBMAPT | |
| SCHEMBL7877627 | 0.80 | HPGD (0.51) | HPGDMEN1KMT2ATHRBMAPT | |
| SCHEMBL7877614 | 0.80 | HPGD (0.51) | HPGDMEN1KMT2ATHRBMAPT | |
| SCHEMBL8661923 | 0.73 | CDK1 (0.43) | HPGDMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9201412 | 0.73 | CDK1 (0.43) | HPGDMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8661476 | 0.72 | CDK1 (0.45) | HPGDMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331506-B1 | Disubstituted methylidene hydrazinophenyl sulfonylureas, process for their production and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 2001-12-18 | — | — | US | disclosed |