Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867247 | 0.87 | OPRL1 (0.34) | OPRL1OPRM1 | |
| SCHEMBL6422341 | 0.80 | F2 (0.38) | OPRL1OPRM1 | |
| SCHEMBL7867236 | 0.79 | F2 (0.34) | — | |
| SCHEMBL3246131 | 0.66 | F2 (0.43) | OPRL1OPRM1 | |
| SCHEMBL7874301 | 0.65 | F2 (0.37) | — | |
| SCHEMBL7874308 | 0.64 | AURKA (0.31) | — | |
| SCHEMBL6426421 | 0.64 | GBA1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL6423013 | 0.63 | GBA1 (0.34) | — | |
| SCHEMBL7874304 | 0.63 | — | — | |
| SCHEMBL7874286 | 0.63 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086122-A1 | PYRAZINONE PROTEASE INHIBITORS | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064446-A1 | PYRAZINONE PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-12-16 | — | — | WO | disclosed |