Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 2/20 | 0.72 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.72 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.72 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.72 |
| ▸ | INSR | P06213 | 1/20 | 0.58 |
| ▸ | IGF1R | P08069 | 1/20 | 0.58 |
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | PSMB8 | P28062 | 7/20 | 0.55 |
| ▸ | GSK3A | P49840 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876111 | 1.00 | PTPN5 (0.72) | PTPN5PTPN7DUSP3PTPN1PTPN22 | |
| SCHEMBL26168538 | 1.00 | PTPN5 (0.72) | PTPN5PTPN7DUSP3PTPN1PTPN22 | |
| SCHEMBL31358863 | 0.90 | PTPN5 (0.70) | PTPN5PTPN7DUSP3PTPN1PTPN22 | |
| SCHEMBL31358813 | 0.90 | PTPN5 (0.64) | PTPN5PTPN7DUSP3PTPN1PTPN22 | |
| SCHEMBL25246954 | 0.89 | PTPN5 (0.68) | PTPN5PTPN7DUSP3PTPN1PTPN22 | |
| SCHEMBL31358848 | 0.89 | PTPN5 (0.68) | PTPN5PTPN7DUSP3PTPN1PTPN22 | |
| SCHEMBL6721181 | 0.88 | PTPN5 (0.71) | PTPN5PTPN7DUSP3PTPN1PTPN22 | |
| SCHEMBL25218896 | 0.87 | PTPN5 (0.69) | PTPN5PTPN7DUSP3PTPN1PTPN22 | |
| SCHEMBL31358719 | 0.84 | PTPN5 (0.63) | PTPN5PTPN7DUSP3PTPN1PTPN22 | |
| SCHEMBL31358810 | 0.84 | PTPN5 (0.63) | PTPN5PTPN7DUSP3PTPN1PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316492-B1 | THERAPY OF INFECTION ONE VIRUS OF THE FLAVIVIRIDAE FAMILY AND DISEASE ASSOCIATED WITH SAID INFECTION BY ADMINISTERING ANTIVIRAL COMPOUND | VIROPHARMA INCORPORATED | 2001-11-13 | — | — | US | disclosed |