SCHEMBL78762

SCHEMBL78762

O=S(=O)(O)c1cc(Cl)ccc1Cl.[Na]

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
MCL1 Q07820 3/20 0.52
TSHR P16473 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
AKR1B1 P15121 1/20 0.47
USP2 O75604 1/20 0.47
MAPK1 P28482 2/20 0.46
GAA P10253 1/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.45
CYP3A4 P08684 2/20 0.44
TP53 P04637 1/20 0.44
ACHE P22303 1/20 0.44
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CNR1 P21554 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384019 0.98 MCL1 (0.53) ALDH1A1MCL1TSHRL3MBTL1HPGD
SCHEMBL198460 0.98 MCL1 (0.53) ALDH1A1MCL1TSHRL3MBTL1HPGD
Water SCHEMBL31261447 0.96 ALDH1A1 (0.52) ALDH1A1MCL1TSHRL3MBTL1HPGD
Hydrochloric Acid SCHEMBL8922332 0.96 ALDH1A1 (0.52) ALDH1A1MCL1TSHRL3MBTL1HPGD
SCHEMBL3695138 0.96 ALDH1A1 (0.52) ALDH1A1MCL1TSHRL3MBTL1HPGD
SCHEMBL5078515 0.96 ALDH1A1 (0.52) ALDH1A1MCL1TSHRL3MBTL1HPGD
SCHEMBL3009009 0.96 ALDH1A1 (0.52) ALDH1A1MCL1TSHRL3MBTL1HPGD
Hydrochloric Acid SCHEMBL11157085 0.96 ALDH1A1 (0.52) ALDH1A1MCL1TSHRL3MBTL1HPGD
SCHEMBL78760 0.96 ALDH1A1 (0.52) ALDH1A1MCL1TSHRL3MBTL1HPGD
Water SCHEMBL28663433 0.96 ALDH1A1 (0.52) ALDH1A1MCL1TSHRL3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6602938-B1 Alkali metal salt of an aromatic sulonic acid SUMITOMO DOW LTD. (JP) 2003-08-05 US claimed
US-4776981-A PHTHALIMIDE COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1988-10-11 US claimed
US-4113695-A Non-opaque flame-retardant polycarbonate composition GENERAL ELECTRIC COMPANY (US) 1978-09-12 US claimed
CN-110267798-B Method of manufacturing an object by additive manufacturing using a polycarbonate build material having improved flow capability 科思创德国股份有限公司 2022-05-27 CN disclosed
CN-107207864-B Flame-resistant moulding compositions containing glass fibres, containing silicone-containing polycarbonate block cocondensates 科思创德国股份有限公司 2021-03-02 CN disclosed
CN-107207863-B Flame-resistant moulding compositions containing silicone-containing polycarbonate block cocondensates 科思创德国股份有限公司 2021-02-19 CN disclosed
WO-2020017113-A1 POLYMER ELECTROLYTE, METHOD FOR PRODUCING SAME, POLYMER ELECTROLYTE MEMBRANE USING SAME, CATALYST LAYER, MEMBRANE/ELECTRODE ASSEMBLY AND FUEL CELL 国立大学法人山梨大学 2020-01-23 WO disclosed
EP-2673318-B1 FLAME RETARDANT, THERMOPLASTIC POLYCARBONATE MOLDING COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2017-07-05 EP disclosed
EP-2460789-B1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-04-19 EP disclosed
US-9079830-B2 Method for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-14 US disclosed
US-20140058025-A1 FLAME RETARDANT, THERMOPLASTIC POLYCARBONATE MOLDING COMPOSITIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-02-27 US disclosed
US-4774273-A ELECTRICAL SUPPLIES, HOUSINGS BAYER AKTIENGESELLSCHAFT (DE) 1988-09-27 US disclosed
US-4661543-A PHTHALIMIDE ADDITIVES BAYER AKTIENGESELLSCHAFT (DE) 1987-04-28 US disclosed
US-4657955-A Flameproofing agents, their preparation and their use for flameproofing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1987-04-14 US disclosed
US-4615832-A Flameproofing agents, their preparation and their use for flameproofing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1986-10-07 US disclosed
US-4506046-A A HALOGEN-FREE AND SULFUR-FREE DIHYDRIC PHENOL, A THIODIPHENOL, AND A SULFONIC ACID SALT GENERAL ELECTRIC COMPANY (US) 1985-03-19 US disclosed
EP-0127818-A1 Improved flame retardant polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1984-12-12 EP disclosed
US-4469833-A MINOR AMOUNTS FO THIODIPHENOL AND ORGANIC SULFONATE GENERAL ELECTRIC COMPANY (US) 1984-09-04 US disclosed
US-4208489-A AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed
US-4113695-A Non-opaque flame-retardant polycarbonate composition GENERAL ELECTRIC COMPANY (US) 1978-09-12 US disclosed