Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342692 | 0.84 | AAK1 (0.33) | AAK1MMP13HDAC1HDAC2HDAC6 | |
| SCHEMBL357909 | 0.84 | AAK1 (0.33) | AAK1MMP13HDAC1HDAC2HDAC6 | |
| SCHEMBL342693 | 0.84 | AAK1 (0.33) | AAK1MMP13HDAC1HDAC2HDAC6 | |
| SCHEMBL1927304 | 0.83 | AAK1 (0.34) | AAK1HDAC1HDAC2HDAC6 | |
| SCHEMBL17277663 | 0.81 | AAK1 (0.32) | AAK1MMP13HDAC1HDAC2HDAC6 | |
| SCHEMBL10126874 | 0.80 | AAK1 (0.33) | AAK1MMP13HDAC1HDAC2HDAC6 | |
| SCHEMBL14831827 | 0.80 | AAK1 (0.33) | AAK1MMP13HDAC1HDAC2HDAC6 | |
| SCHEMBL14952039 | 0.80 | AAK1 (0.33) | AAK1MMP13HDAC1HDAC2HDAC6 | |
| SCHEMBL18796420 | 0.78 | CA14 (0.41) | AAK1MMP13HDAC1HDAC2HDAC6 | |
| SCHEMBL9455522 | 0.78 | CA14 (0.41) | AAK1MMP13HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329502-B1 | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS; TREATMENT OF AIDS (ACQUIRED IMMUNE DEFICIENCY SYNDROME) | JAPAN ENERGY CORPORATION (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6313094-B1 | COMPOSITION FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | JAPAN ENERGY CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0490667-B1 | HIV protease inhibitors | JAPAN ENERGY CORP (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0490667-A2 | HIV protease inhibitors | JAPAN ENERGY CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |