Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291597 | 0.94 | MEN1 (0.43) | MEN1KMT2APPARACYP1A2CYP3A4 | |
| SCHEMBL9293041 | 0.82 | MEN1 (0.46) | MEN1KMT2APPARACYP1A2CYP3A4 | |
| SCHEMBL11596659 | 0.82 | MIF (0.47) | MEN1KMT2APPARACYP1A2CYP3A4 | |
| SCHEMBL340836 | 0.81 | KCNN4 (0.52) | KMT2ACYP1A2CYP2D6MAPTCYP2C19 | |
| SCHEMBL10334663 | 0.80 | CES1 (0.41) | MEN1KMT2APPARACYP1A2CYP3A4 | |
| SCHEMBL6785896 | 0.80 | KCNN4 (0.44) | MEN1KMT2AMAPTEDNRBEDNRA | |
| SCHEMBL11442181 | 0.80 | KMT2A (0.40) | MEN1KMT2ACYP1A2MAPTPOLB | |
| SCHEMBL11272041 | 0.79 | MEN1 (0.51) | MEN1KMT2APPARACYP1A2CYP3A4 | |
| SCHEMBL7171746 | 0.79 | MIF (0.46) | MEN1KMT2APPARACYP1A2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL9292403 | 0.79 | KCNN4 (0.50) | KMT2ACYP1A2CYP2D6MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205087-A | ANTIARTHRITIC AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-05-27 | — | — | US | claimed |
| US-6329502-B1 | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS; TREATMENT OF AIDS (ACQUIRED IMMUNE DEFICIENCY SYNDROME) | JAPAN ENERGY CORPORATION (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6313094-B1 | COMPOSITION FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | JAPAN ENERGY CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0490667-B1 | HIV protease inhibitors | JAPAN ENERGY CORP (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0490667-A2 | HIV protease inhibitors | JAPAN ENERGY CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-4205087-A | ANTIARTHRITIC AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-05-27 | — | — | US | disclosed |
| US-4205087-A | ANTIARTHRITIC AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-05-27 | — | — | US | disclosed |