Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174341 | 0.82 | ALDH1A1 (0.39) | MEN1KMT2ACYP3A4CYP2D6MAPT | |
| SCHEMBL7876582 | 0.79 | MEN1 (0.47) | MEN1KMT2APPARACYP3A4CYP2D6 | |
| SCHEMBL11596659 | 0.77 | MIF (0.47) | MEN1KMT2APPARACYP3A4CYP2D6 | |
| SCHEMBL7171746 | 0.75 | MIF (0.46) | MEN1KMT2APPARACYP3A4CYP2D6 | |
| SCHEMBL9291597 | 0.75 | MEN1 (0.43) | MEN1KMT2APPARACYP3A4CYP2D6 | |
| SCHEMBL11598088 | 0.72 | MEN1 (0.66) | MEN1KMT2APPARACYP3A4CYP2D6 | |
| SCHEMBL10334690 | 0.71 | CYP3A4 (0.46) | MEN1KMT2APPARACYP3A4CYP2D6 | |
| SCHEMBL11168281 | 0.70 | KMT2A (0.50) | MEN1KMT2APPARACYP3A4CYP2D6 | |
| SCHEMBL22722998 | 0.70 | KMT2A (0.50) | MEN1KMT2APPARACYP3A4CYP2D6 | |
| SCHEMBL22722989 | 0.70 | KMT2A (0.50) | MEN1KMT2APPARACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4220663-A | Combating pests with benzyl phenyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-02 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |
| US-4145439-A | NEMATOCIDES, FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |
| US-4058604-A | OR ACARICIDALLY ACTIVE SUBSTANCES | CIBA-GEIGY AG (CH) | 1977-11-15 | — | — | US | disclosed |
| US-4048315-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |
| US-3980799-A | OR ACARICIDALLY ACTIVE SUBSTANCES | CIBA-GEIGY AG (CH) | 1976-09-14 | — | — | US | disclosed |
| US-3940412-A | 2,4,5-Trichloro- and 2,4,5-tribromoimidazole derivatives and pesticidal compositions containing them | CIBA-GEIGY AG (CH) | 1976-02-24 | — | — | US | disclosed |
| US-3932632-A | Insecticidal compositions containing an organophosphorus compound and a thiolcarbamate | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |