SCHEMBL7876637

SCHEMBL7876637

[CH2]C(NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.57
PPARA Q07869 3/20 0.54
ATM Q13315 1/20 0.51
CTSS P25774 4/20 0.51
CTSL P07711 2/20 0.50
MAPT P10636 2/20 0.50
PPARG P37231 2/20 0.49
CTSK P43235 3/20 0.49
CTSB P07858 1/20 0.49
ACE P12821 1/20 0.47
KLK5 Q9Y337 2/20 0.47
KLK7 P49862 1/20 0.47
POLB P06746 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA7 P43166 1/20 0.46
CA14 Q9ULX7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5571757 0.88 SYK (0.54) SYKPPARAATMCTSSCTSL
SCHEMBL22433329 0.85 SYK (0.54) SYKPPARAATMCTSSCTSL
SCHEMBL1463134 0.84 POLB (0.58) SYKPPARAATMCTSSCTSL
SCHEMBL648574 0.84 POLB (0.58) SYKPPARAATMCTSSCTSL
SCHEMBL7512116 0.84 POLB (0.58) SYKPPARAATMCTSSCTSL
SCHEMBL16488769 0.84 CTSS (0.56) SYKPPARAATMCTSSCTSL
SCHEMBL20993818 0.84 CTSS (0.56) SYKPPARAATMCTSSCTSL
SCHEMBL3133276 0.84 CTSS (0.56) SYKPPARAATMCTSSCTSL
SCHEMBL6181712 0.84 CTSS (0.56) SYKPPARAATMCTSSCTSL
SCHEMBL13827783 0.84 CTSS (0.56) SYKPPARAATMCTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO disclosed