⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25378286 | 0.74 | — | — | |
| SCHEMBL22016090 | 0.74 | — | — | |
| SCHEMBL11894064 | 0.74 | — | — | |
| SCHEMBL5985575 | 0.73 | — | — | |
| SCHEMBL4492972 | 0.73 | — | — | |
| SCHEMBL27603451 | 0.73 | — | — | |
| SCHEMBL48395 | 0.73 | — | — | |
| SCHEMBL19692381 | 0.73 | — | — | |
| SCHEMBL4726442 | 0.73 | — | — | |
| SCHEMBL27952255 | 0.73 | PIK3CB (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329522-B1 | GLYCOSYLATING PURINE OR PYRIMIDINE BASE OR ANALOGUE THEREOF WITH OXATHIOLAN OR DITHIOLAN DERIVATIVE IN PRESENCE OF LEWIS ACID CATALYST | GLAXO GROUP LIMITED (GB) | 2001-12-11 | — | — | US | disclosed |
| US-6051709-A | Process for the diastereoselective synthesis of nucleoside analogues | GLAXO GROUP LIMITED (GB) | 2000-04-18 | — | — | US | disclosed |
| EP-0757684-B1 | PROCESS FOR THE DIASTEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES | GLAXO GROUP LTD (GB) | 1999-06-16 | — | — | EP | disclosed |
| EP-0757684-A1 | PROCESS FOR THE DIASTEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES | GLAXO GROUP LIMITED (GB) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029174-A1 | PROCESS FOR THE DIASTEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES | GLAXO GROUP LIMITED (GB) | 1995-11-02 | — | — | WO | disclosed |