Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634941 | 0.88 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL27657804 | 0.84 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL16107215 | 0.84 | TSHR (0.43) | TSHRALDH1A1 | |
| SCHEMBL25125852 | 0.84 | TSHR (0.43) | TSHRALDH1A1 | |
| SCHEMBL29287268 | 0.81 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL18698899 | 0.80 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL14137863 | 0.79 | MEN1 (0.34) | TSHRALDH1A1 | |
| SCHEMBL1817041 | 0.77 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL15978448 | 0.77 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL11246030 | 0.75 | TSHR (0.39) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326387-B1 | NEUROTROPIC COMPOUND | VERTEX PHARMACEUTICALS INCORPORATED | 2001-12-04 | — | — | US | disclosed |
| CN-1202104-A | Methods and compositions for stimulating neurite growth | VERTEX PHARMA (US) | 1998-12-16 | — | — | CN | disclosed |