Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPS1 | P31327 | 14/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17400780 | 0.87 | CPS1 (0.51) | CPS1MTOR | |
| SCHEMBL7871468 | 0.81 | CPS1 (0.57) | CPS1MTORPDE2ALMNAHTT | |
| SCHEMBL7870107 | 0.79 | CPS1 (0.54) | CPS1MTORLMNAHTTMAPT | |
| SCHEMBL20460504 | 0.75 | HPGD (0.59) | CPS1PDE2ALMNAHTTMAPT | |
| SCHEMBL7872416 | 0.74 | CPS1 (0.57) | CPS1PDE2ALMNAHTTMAPT | |
| SCHEMBL18010744 | 0.74 | CPS1 (0.57) | CPS1LMNAHTTMAPTTSHR | |
| SCHEMBL7878686 | 0.74 | CPS1 (0.60) | CPS1PDE2ALMNAHTTMAPT | |
| SCHEMBL7875944 | 0.73 | TP53 (0.53) | CPS1MTORPDE2ALMNAHTT | |
| SCHEMBL12205464 | 0.73 | CPS1 (0.58) | CPS1PDE2ALMNAHTTMAPT | |
| SCHEMBL7877653 | 0.72 | CYP46A1 (0.61) | CPS1PDE2ALMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122069-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |