SCHEMBL7877027

SCHEMBL7877027

CCCCCCCC(F)CCO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
MAPT P10636 2/20 0.48
ALDH1A1 P00352 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
TSHR P16473 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.43
OPRM1 P35372 1/20 0.42
CYP2D6 P10635 2/20 0.42
SPHK1 Q9NYA1 2/20 0.42
GMNN O75496 1/20 0.42
POLB P06746 1/20 0.42
THPO P40225 1/20 0.42
MTOR P42345 1/20 0.42
BLM P54132 1/20 0.42
KDM4E B2RXH2 1/20 0.42
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11875896 1.00 LMNA (0.50) LMNAMAPTALDH1A1HSD17B10MEN1
SCHEMBL8406028 1.00 LMNA (0.50) LMNAMAPTALDH1A1HSD17B10MEN1
SCHEMBL8406027 1.00 LMNA (0.50) LMNAMAPTALDH1A1HSD17B10MEN1
SCHEMBL8580078 1.00 LMNA (0.50) LMNAMAPTALDH1A1HSD17B10MEN1
SCHEMBL7874367 0.98 LMNA (0.46) LMNAMAPTALDH1A1HSD17B10MEN1
SCHEMBL9439747 0.91 LMNA (0.62) LMNAMAPTALDH1A1HSD17B10MEN1
SCHEMBL8732382 0.91 LMNA (0.62) LMNAMAPTALDH1A1HSD17B10MEN1
SCHEMBL28685742 0.91 LMNA (0.62) LMNAMAPTALDH1A1HSD17B10MEN1
SCHEMBL6241308 0.91 LMNA (0.62) LMNAMAPTALDH1A1HSD17B10MEN1
SCHEMBL7083732 0.91 LMNA (0.62) LMNAMAPTALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6328980-B1 Emulsion composition comprising a fluorohydrocarbon compound and a method for preparing L'OREAL (FR) 2001-12-11 US disclosed
US-6322800-B1 INCORPORATING INTO FATTY PHASE A FLUOROESTER LIKE 2(F-OCTYL)ETHYL AS A STABILIZING AGENT; USED IN COSMETIC, HYGIENE OR PHARMACEUTICAL COMPOSITION L'OREAL S.A. (FR) 2001-11-27 US disclosed
US-5846516-A Perfluoroalkylated amphiphilic phosphorus compounds: preparation and biomedical applications ALLIANCE PHARMACEUTIAL CORP. (US) 1998-12-08 US disclosed
US-5753240-A PERFLUORINATED ALKYL-N-ALKYLOXYCARBONYL-ALKYLCARBAMATES USED AS THICKENING AGENTS IN DRUGS AND COSMETICS L'OREAL (FR) 1998-05-19 US disclosed
US-5679459-A USEFUL AS DELIVERY SYSTEMS FOR THERAPEUTIC AGENTS ALLIANCE PHARMACEUTICAL CORP. (US) 1997-10-21 US disclosed
EP-0428720-B1 OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE MERCK PATENT GMBH (DE) 1995-03-22 EP disclosed
US-5393459-A Optically active compounds, and a liquid-crystalline phase MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-28 US disclosed
US-5344930-A Blood substitutes to carry oxygen ALLIANCE PHARMACEUTICAL CORP. (US) 1994-09-06 US disclosed
EP-0478686-B1 FLUORINE AND PHOSPHOROUS-CONTAINING AMPHIPHILIC MOLECULES WITH SURFACTANT PROPERTIES APPLICATIONS ET TRANSFERTS DE TECHNOLOGIES AVANCEES ATTA (FR) 1993-08-11 EP disclosed
WO-1992021688-A1 NEW PERFLUOROALKYLATED AMPHIPHILIC PHOSPHORUS COMPOUNDS: PREPARATION AND BIOMEDICAL APPLICATIONS S.A. A.T.T.A. APPLICATIONS ET TRANSFERTS DE TECHN OLOGIES AVANCEES (FR) 1992-12-10 WO disclosed
EP-0255443-B1 NEW POLYHYDROXYLATED AND HIGHLY FLUORINATED COMPOUNDS, THEIR PREPARATION AND THEIR USE AS SURFACTANTS ATTA (FR) 1992-10-14 EP disclosed
EP-0478686-A1 FLUORINE AND PHOSPHOROUS-CONTAINING AMPHIPHILIC MOLECULES WITH SURFACTANT PROPERTIES. ATTA (FR) 1992-04-08 EP disclosed
EP-0428720-A1 OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE. MERCK PATENT GMBH (DE) 1991-05-29 EP disclosed
US-4985550-A Sugar derivatives, oxygen carriers, artificial blood ALLIANCE PHARMACEUTICAL CORP. (US) 1991-01-15 US disclosed
WO-1990015807-A1 FLUORINE AND PHOSPHOROUS-CONTAINING AMPHIPHILIC MOLECULES WITH SURFACTANT PROPERTIES APPLICATIONS ET TRANSFERTS DE TECHNOLOGIES AVANCÉES (FR) 1990-12-27 WO disclosed
WO-1990013611-A2 OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-11-15 WO disclosed
EP-0255443-A1 New polyhydroxylated and highly fluorinated compounds, their preparation and their use as surfactants ATTA (FR) 1988-02-03 EP disclosed