SCHEMBL7877053

SCHEMBL7877053

CC[C@@H](N)CCCNC(C)=N

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.34
RRM1 P23921 1/20 0.32
SIRT6 Q8N6T7 1/20 0.30
SIRT1 Q96EB6 1/20 0.30
GNAI3 P08754 1/20 0.30
GNAO1 P09471 1/20 0.30
GNAI1 P63096 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8075932 0.94 DPP7 (0.37) DPP7RRM1SIRT6SIRT1GNAI3
SCHEMBL171399 0.84 MEN1 (0.40) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL7158448 0.84 MEN1 (0.40) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL18822222 0.84 MEN1 (0.40) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL19368433 0.82 DPP7 (0.33) DPP7RRM1
SCHEMBL8067951 0.81 DPP7 (0.47) DPP7RRM1SIRT6SIRT1GNAI3
SCHEMBL8068088 0.79 OPRM1 (0.39) DPP7RRM1
SCHEMBL16138483 0.78 MEN1 (0.43) DPP7RRM1SIRT6SIRT1GNAI3
SCHEMBL8067814 0.78 DPP7 (0.33) DPP7RRM1SIRT6SIRT1GNAI3
SCHEMBL18085377 0.78 KDM4E (0.41) DPP7RRM1SIRT6SIRT1GNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010146578-A2 PEPTIDE THERAPY FOR INCREASING PLATELET LEVELS BIOKINE THERAPEUTICS LTD. (IL) 2010-12-23 WO disclosed