Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.54 |
| ▸ | REN | P00797 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PEPD | P12955 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566638 | 1.00 | ACE (0.54) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL10486860 | 0.76 | ACE (0.51) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL1432569 | 0.76 | ACE (0.49) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL1881293 | 0.76 | ACE (0.49) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL1432340 | 0.76 | ACE (0.49) | ACERENLMNAHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL27214127 | 0.74 | RAB9A (0.38) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL27577641 | 0.74 | RAB9A (0.41) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL7207958 | 0.74 | ACE (0.44) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL3803835 | 0.74 | ACE (0.44) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL27496955 | 0.73 | ACE (0.44) | ACERENLMNAHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6171232-B1 | A DRUG DELIVERY OF NITROVASODILATORS BY A THIOL GROUP AGENT LOADED ONTO A MEDICAL DEVICE SUCH AS A STENT OR A CATHETER | CORDIS CORPORATION | 2001-01-09 | — | — | US | disclosed |