Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.67 |
| ▸ | MMP2 | P08253 | 2/20 | 0.60 |
| ▸ | MMP9 | P14780 | 2/20 | 0.60 |
| ▸ | MMP12 | P39900 | 2/20 | 0.60 |
| ▸ | CPA1 | P15085 | 2/20 | 0.55 |
| ▸ | CPB1 | P15086 | 1/20 | 0.55 |
| ▸ | CPA3 | P15088 | 1/20 | 0.55 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877341 | 1.00 | KMO (0.67) | KMOMMP2MMP9MMP12CPA1 | |
| SCHEMBL728129 | 1.00 | KMO (0.67) | KMOMMP2MMP9MMP12CPA1 | |
| SCHEMBL728320 | 0.80 | KMO (1.00) | KMOCPA1CPB1CPA3CPB2 | |
| SCHEMBL3667472 | 0.80 | KMO (1.00) | KMOCPA1CPB1CPA3CPB2 | |
| SCHEMBL727440 | 0.80 | KMO (1.00) | KMOCPA1CPB1CPA3CPB2 | |
| SCHEMBL12350244 | 0.78 | KMO (0.54) | KMOMEN1KMT2APPARGPPARA | |
| SCHEMBL10778650 | 0.77 | KMO (0.63) | KMO | |
| SCHEMBL3670804 | 0.77 | KMO (0.48) | KMO | |
| SCHEMBL726890 | 0.77 | KMO (0.48) | KMO | |
| SCHEMBL728166 | 0.77 | KMO (0.48) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323240-B1 | HALOGENATED DERIVATIVES AS ENZYME INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 2001-11-27 | — | — | US | disclosed |