⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL985970 | 0.90 | — | — | |
| SCHEMBL16768948 | 0.86 | HIF1A (0.38) | — | |
| SCHEMBL11288268 | 0.77 | — | — | |
| SCHEMBL16004661 | 0.77 | FAAH (0.37) | — | |
| SCHEMBL16004662 | 0.77 | FAAH (0.37) | — | |
| SCHEMBL3535726 | 0.76 | HIF1A (0.41) | — | |
| SCHEMBL7643702 | 0.76 | FAAH (0.31) | — | |
| SCHEMBL18282347 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL11351354 | 0.75 | — | — | |
| SCHEMBL22044036 | 0.74 | HIF1A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108840848-B | Preparation method and application of coumarin hapten and antigen | 中国烟草总公司郑州烟草研究院 | 2021-11-23 | — | — | CN | claimed |
| US-4374995-A | Process for the production of tryptophane-hydantoin | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1983-02-22 | — | — | US | claimed |
| CN-108840848-B | Preparation method and application of coumarin hapten and antigen | 中国烟草总公司郑州烟草研究院 | 2021-11-23 | — | — | CN | disclosed |
| CN-108956993-B | Test strip for detecting coumarin and preparation method and application thereof | 中国烟草总公司郑州烟草研究院 | 2021-03-12 | — | — | CN | disclosed |
| CN-108956975-B | Enzyme linked immunosorbent assay kit for detecting coumarin and application thereof | 中国烟草总公司郑州烟草研究院 | 2021-03-12 | — | — | CN | disclosed |
| CN-108680738-B | Time-resolved fluorescence immunochromatographic test strip for detecting coumarin and preparation method and application thereof | 中国烟草总公司郑州烟草研究院 | 2020-09-22 | — | — | CN | disclosed |
| CN-105712842-B | The separating and extracting process of 1,3- propylene glycol in a kind of zymotic fluid | 中国石油化工股份有限公司 | 2018-06-19 | — | — | CN | disclosed |
| CN-105712841-B | A kind of method of the propane diols of the separation and Extraction from zymotic fluid 1,3 | 中国石油化工股份有限公司 | 2017-10-27 | — | — | CN | disclosed |
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |
| EP-1083903-A4 | BRIDGED INDENOPYRROLOCARBAZOLES | CEPHALON INC (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1083903-A1 | BRIDGED INDENOPYRROLOCARBAZOLES | CEPHALON, INC. (US) | 2001-03-21 | — | — | EP | disclosed |
| US-4376864-A | Cyclic acetals of glutamic acid-γ-semialdehyde, process for their production and use | DEGUSSA AG (DE) | 1983-03-15 | — | — | US | disclosed |
| US-4374995-A | Process for the production of tryptophane-hydantoin | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1983-02-22 | — | — | US | disclosed |
| EP-0052200-A1 | Cyclic acetals of N-acylated glutamic acid gamma-semialdehydes, process for their preparation and their use | Degussa Aktiengesellschaft (DE) | 1982-05-26 | — | — | EP | disclosed |
| EP-0052201-A1 | Cyclic acetals of glutamic acid gamma-semialdehyde, process for their preparation and their use | Degussa Aktiengesellschaft (DE) | 1982-05-26 | — | — | EP | disclosed |
| EP-0052199-A1 | Process for producing tryptophane hydantoin | Degussa Aktiengesellschaft (DE) | 1982-05-26 | — | — | EP | disclosed |
| US-4255587-A | CARBONYLATION OF 2,6-DIALKYLANILINES USING AN OXO-SUBSTITUTED ESTER FOLLOWED BY CATALYTIC HYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 1981-03-10 | — | — | US | disclosed |
| EP-0003304-A2 | Process for the preparation of N-substituted 2,6-dialkyl anilines | BASF Aktiengesellschaft (DE) | 1979-08-08 | — | — | EP | disclosed |
| US-4079064-A | HYDROFORMYLATION OF 2-VINYL-1,3-DIOXANES WITH HYDROGEN AND CARBON MONOXIDE | CELANESE CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
| US-4079064-A | HYDROFORMYLATION OF 2-VINYL-1,3-DIOXANES WITH HYDROGEN AND CARBON MONOXIDE | CELANESE CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |