SCHEMBL7866062

SCHEMBL7866062

CON=C(Cc1ccccc1)C(C)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 3/20 0.52
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
AKR1B1 P15121 1/20 0.47
L3MBTL1 Q9Y468 5/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
THRB P10828 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HDAC3 O15379 3/20 0.44
HDAC4 P56524 3/20 0.44
HDAC1 Q13547 3/20 0.44
HDAC7 Q8WUI4 3/20 0.44
HDAC2 Q92769 3/20 0.44
HDAC10 Q969S8 3/20 0.44
HDAC11 Q96DB2 3/20 0.44
HDAC8 Q9BY41 3/20 0.44
HDAC6 Q9UBN7 3/20 0.44
HDAC9 Q9UKV0 3/20 0.44
HDAC5 Q9UQL6 3/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29346014 0.89 CTBP2 (0.61) CTBP2CES2CES1AKR1B1L3MBTL1
SCHEMBL11888718 0.89 CTBP2 (0.61) CTBP2CES2CES1AKR1B1L3MBTL1
SCHEMBL7875369 0.84 CTBP2 (0.50) CTBP2CES2CES1AKR1B1L3MBTL1
SCHEMBL7875372 0.84 CTBP2 (0.50) CTBP2CES2CES1AKR1B1L3MBTL1
SCHEMBL19994305 0.82 CTBP2 (0.49) CTBP2CES2CES1AKR1B1L3MBTL1
SCHEMBL7877784 0.81 CTBP2 (0.71) CTBP2CES2CES1AKR1B1HIF1A
SCHEMBL7877787 0.81 CTBP2 (0.71) CTBP2CES2CES1AKR1B1HIF1A
SCHEMBL27570436 0.79 CTBP2 (0.53) CTBP2L3MBTL1SMN1; SMN2THRBTDP1
SCHEMBL19433075 0.79 MAPT (0.49) CTBP2CES2CES1AKR1B1L3MBTL1
SCHEMBL10177918 0.79 MAPT (0.49) CTBP2CES2CES1AKR1B1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1206914-C Pesticide containing 0-benzyl oximeether derivative and its use NOVARTIS AG (CH) 2005-06-22 CN disclosed
CN-1075490-C O-benzyl oxime ether derivatives and their use in crop protection compositions BAYER AG (DE) 2001-11-28 CN disclosed
US-6319925-B1 MICROBICIDAL, ACARICIDAL AND INSECTICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 2001-11-20 US disclosed
CN-1309898-A Pesticide containing 0-benzyl oximeether derivative and its use NOVARTIS AG (CH) 2001-08-29 CN disclosed
EP-0848701-B1 O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE IN CROP PROTECTION COMPOSITIONS NOVARTIS AG (CH) 2000-05-17 EP disclosed
CN-1189150-A O-benzyl oxime ether derivatives and their use in crop protection compositions NOVATIS LTD (CH) 1998-07-29 CN disclosed
EP-0848701-A1 O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE IN CROP PROTECTION COMPOSITIONS Novartis AG (CH) 1998-06-24 EP disclosed
WO-1997001530-A1 O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE IN CROP PROTECTION COMPOSITIONS NOVARTIS AG (CH) 1997-01-16 WO disclosed