Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877618 | 0.82 | CDK1 (0.48) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL5847237 | 0.81 | CDK1 (0.54) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL5847235 | 0.81 | CDK1 (0.54) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL9080269 | 0.79 | CDK1 (0.62) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL9197645 | 0.79 | CDK1 (0.55) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL9202913 | 0.77 | CDK1 (0.55) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL8664968 | 0.76 | CDK1 (0.51) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL9284934 | 0.75 | CDK1 (0.52) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL7877627 | 0.75 | HPGD (0.51) | CDK1GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL7877614 | 0.75 | HPGD (0.51) | CDK1GAAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331506-B1 | Disubstituted methylidene hydrazinophenyl sulfonylureas, process for their production and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 2001-12-18 | — | — | US | disclosed |