Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806109 | 0.85 | CDK1 (0.44) | CDK1GAAKDM4ENPC1MAPT | |
| SCHEMBL9197645 | 0.85 | CDK1 (0.55) | CDK1GAACYP1A2TP53GLA | |
| SCHEMBL5847235 | 0.83 | CDK1 (0.54) | CDK1GAAALDH1A1KDM4ENPC1 | |
| SCHEMBL5847237 | 0.83 | CDK1 (0.54) | CDK1GAAALDH1A1KDM4ENPC1 | |
| SCHEMBL8660204 | 0.83 | CDK1 (0.43) | CDK1GAATUBB4ATUBBTUBA3C | |
| SCHEMBL9080269 | 0.83 | CDK1 (0.62) | CDK1GAATUBB4ATUBBTUBA3C | |
| SCHEMBL10341393 | 0.82 | GAA (0.52) | CDK1GAAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9202913 | 0.81 | CDK1 (0.55) | CDK1GAACYP1A2TP53GLA | |
| SCHEMBL11385667 | 0.78 | CDK1 (0.57) | CDK1GAAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9387441 | 0.78 | GAA (0.52) | CDK1GAACYP1A2TP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723409-A | Intermediates for the preparation of phenylsulfonylurea herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1998-03-03 | — | — | US | disclosed |
| US-5449812-A | Substituted benzenesulfonamide derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-12 | — | — | US | disclosed |
| EP-0666852-A1 | NEW PHENYLSULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS. | HOECHST SCHERING AGREVO GMBH (DE) | 1995-08-16 | — | — | EP | disclosed |
| WO-1994010154-A1 | NEW PHENYLSULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1994-05-11 | — | — | WO | disclosed |