Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879497 | 1.00 | HTR1A (0.37) | HTR1AADRA1DADRA1AADRA1BSOAT1 | |
| SCHEMBL7878062 | 0.92 | SOAT1 (0.37) | HTR1AADRA1DADRA1AADRA1BSOAT1 | |
| SCHEMBL7878073 | 0.91 | CYP3A4 (0.39) | SOAT1PTPN11CYP3A4CYP2D6THRA | |
| SCHEMBL7882429 | 0.91 | CYP3A4 (0.39) | SOAT1PTPN11CYP3A4CYP2D6THRA | |
| SCHEMBL6944139 | 0.82 | SOAT1 (0.41) | SOAT1CYP3A4CYP2D6 | |
| SCHEMBL7877662 | 0.82 | CYP3A4 (0.39) | SOAT1PTPN11CYP3A4CYP2D6THRA | |
| SCHEMBL7871760 | 0.82 | CYP3A4 (0.39) | SOAT1PTPN11CYP3A4CYP2D6THRA | |
| SCHEMBL9405922 | 0.81 | GSTP1 (0.46) | HTR1AADRA1DADRA1AADRA1BPTPN11 | |
| SCHEMBL7875959 | 0.81 | CYP3A4 (0.39) | SOAT1PTPN11CYP3A4CYP2D6 | |
| SCHEMBL7879454 | 0.80 | CYP3A4 (0.38) | SOAT1PTPN11CYP3A4CYP2D6THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883618-B1 | DIFLUOROPHENYL PYRIMIDYL PYRIDINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-05-16 | — | — | EP | disclosed |
| US-6022492-A | FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICE | HOESCHT RESEARCH & TECHNOLOGY DEUTCHLAND GMBH & CO. (DE) | 2000-02-08 | — | — | US | disclosed |
| EP-0883618-A1 | DIFLUOROPHENYL PYRIMIDYL PYRIDINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTAL MIXTURES | Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997024351-A1 | DIFLUOROPHENYL PYRIMIDYL PYRIDINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTAL MIXTURES | HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO.KG (DE) | 1997-07-10 | — | — | WO | disclosed |