Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878158 | 0.84 | PDCD1 (0.32) | — | |
| SCHEMBL5517962 | 0.80 | CA12 (0.31) | CA12CA1CA2CA9 | |
| SCHEMBL9068967 | 0.77 | MAPT (0.30) | — | |
| SCHEMBL8631698 | 0.76 | MAPT (0.32) | — | |
| SCHEMBL9069578 | 0.75 | — | — | |
| SCHEMBL7602549 | 0.75 | — | — | |
| SCHEMBL9068909 | 0.75 | ALDH1A1 (0.30) | — | |
| SCHEMBL8630898 | 0.75 | MAPT (0.31) | — | |
| SCHEMBL8634951 | 0.75 | ALDH1A1 (0.30) | — | |
| SCHEMBL9069720 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177376-B1 | REACTING METALLOCENE WITH ORGANOLITHIUM COMPOUND AND GRIGNARD COMPOUND, ACTIVATION, CONTACTING WITH SUPPORT | TARGOR GMBH (DE) | 2001-01-23 | — | — | US | disclosed |