Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717362 | 0.91 | DGAT1 (0.61) | DGAT1SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL7717358 | 0.91 | DGAT1 (0.61) | DGAT1SMN1; SMN2LMNAMAPTALDH1A1 | |
| Water SCHEMBL8931192 | 0.90 | DGAT1 (0.60) | DGAT1SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL7883247 | 0.90 | DGAT1 (0.71) | DGAT1SMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL8931684 | 0.87 | DGAT1 (0.60) | DGAT1SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL8809855 | 0.86 | DGAT1 (0.57) | DGAT1SMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL8815535 | 0.85 | DGAT1 (0.53) | DGAT1SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL7893726 | 0.85 | DGAT1 (0.54) | DGAT1SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL8755552 | 0.85 | DGAT1 (0.59) | DGAT1SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL9285996 | 0.84 | DGAT1 (0.54) | DGAT1SMN1; SMN2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754180-B1 | ANTI-HELICOBACTER ESTER AND CARBAMATE DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA NV (BE) | 2001-10-31 | — | — | EP | claimed |
| EP-0754180-A1 | ANTI-HELICOBACTER ESTER AND CARBAMATE DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-01-22 | — | — | EP | claimed |
| WO-1995027704-A1 | ANTI-HELICOBACTER ESTER AND CARBAMATE DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-10-19 | — | — | WO | claimed |
| EP-0754180-B1 | ANTI-HELICOBACTER ESTER AND CARBAMATE DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA NV (BE) | 2001-10-31 | — | — | EP | disclosed |