Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655900 | 0.98 | TLR9 (0.50) | TLR9MCHR1CTSKG6PDALDH1A1 | |
| SCHEMBL4391248 | 0.87 | TLR9 (0.57) | TLR9MCHR1CTSKG6PDALDH1A1 | |
| SCHEMBL7330132 | 0.84 | TDP1 (0.47) | TLR9ALDH1A1CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL5077216 | 0.82 | EPHX2 (0.47) | TLR9ALDH1A1TDP1TSHR | |
| SCHEMBL4398844 | 0.79 | TLR9 (0.61) | TLR9CTSKG6PDALDH1A1CYP2C9 | |
| SCHEMBL7768688 | 0.77 | TLR9 (0.46) | TLR9MCHR1CTSKG6PDALDH1A1 | |
| Hexane SCHEMBL7122950 | 0.73 | MCHR1 (0.53) | MCHR1G6PDALDH1A1CYP2C9CYP2C19 | |
| Hexane SCHEMBL11658743 | 0.73 | MCHR1 (0.53) | TLR9MCHR1G6PDALDH1A1CYP2C9 | |
| SCHEMBL28433005 | 0.72 | TLR9 (0.44) | TLR9MCHR1CTSKALDH1A1CYP2C9 | |
| Decane SCHEMBL17004268 | 0.72 | MCHR1 (0.56) | MCHR1G6PDALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573218-B1 | 4-Carboxyimidazoles as angiotensin II antagonists and their thrapeutic use | SANKYO CO (JP) | 2001-03-07 | — | — | EP | disclosed |