Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077216 | 0.98 | EPHX2 (0.47) | TDP1PSIP1EPHX2TLR9ABCB1 | |
| SCHEMBL29171177 | 0.89 | TDP1 (0.45) | TDP1PSIP1EPHX2TLR9ABCB1 | |
| SCHEMBL4394025 | 0.86 | PSIP1 (0.50) | TDP1PSIP1TLR9ABCB1ALDH1A1 | |
| SCHEMBL7878733 | 0.84 | TLR9 (0.52) | TDP1TLR9ALDH1A1TSHRCYP1A2 | |
| SCHEMBL8655900 | 0.82 | TLR9 (0.50) | TDP1TLR9ALDH1A1TSHRCYP1A2 | |
| SCHEMBL8366438 | 0.82 | TLR9 (0.50) | TDP1PSIP1EPHX2TLR9ABCB1 | |
| SCHEMBL8366439 | 0.82 | TLR9 (0.50) | TDP1PSIP1EPHX2TLR9ABCB1 | |
| SCHEMBL6901744 | 0.81 | EPHX2 (0.51) | TDP1PSIP1EPHX2TLR9ABCB1 | |
| SCHEMBL6901746 | 0.81 | EPHX2 (0.51) | TDP1PSIP1EPHX2TLR9ABCB1 | |
| SCHEMBL132867 | 0.80 | TLR9 (0.42) | TDP1PSIP1EPHX2TLR9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355583-A2 | Cardiotonics | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |