Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPS1 | P31327 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878686 | 0.86 | CPS1 (0.60) | CPS1HTTLMNAMAPTTSHR | |
| SCHEMBL20460441 | 0.84 | RXFP1 (0.50) | HTTLMNAMAPTTSHRRXFP1 | |
| SCHEMBL12205464 | 0.84 | CPS1 (0.58) | CPS1HTTLMNAMAPTTSHR | |
| SCHEMBL14174297 | 0.84 | RXFP1 (0.50) | HTTLMNARXFP1CHEK1AURKA | |
| SCHEMBL7872416 | 0.83 | CPS1 (0.57) | CPS1HTTLMNAMAPTTSHR | |
| SCHEMBL18010744 | 0.83 | CPS1 (0.57) | CPS1HTTLMNAMAPTTSHR | |
| SCHEMBL22425350 | 0.83 | HSP90AA1 (0.57) | RXFP1CHEK1AURKADAPK3JAK2 | |
| Hydrochloric Acid SCHEMBL2849329 | 0.83 | KDM4E (0.58) | CPS1HTTRXFP1HRH4HSP90AA1 | |
| SCHEMBL20750338 | 0.82 | CPS1 (0.49) | CPS1RXFP1HRH4HSP90AA1KDM4E | |
| SCHEMBL7872429 | 0.82 | MAPT (0.57) | CPS1HTTLMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122069-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |