Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809655 | 0.92 | TSHR (0.65) | TSHRGABRA1GABRB2POLBBCHE | |
| SCHEMBL296591 | 0.90 | TSHR (0.68) | TSHRGABRA1GABRB2POLBBCHE | |
| SCHEMBL29860994 | 0.90 | TSHR (0.68) | TSHRGABRA1GABRB2POLBBCHE | |
| Ammonia Solution, Strong SCHEMBL28876892 | 0.88 | TSHR (0.65) | TSHRGABRA1GABRB2POLBBCHE | |
| Bicarbonate SCHEMBL7033903 | 0.84 | TSHR (0.61) | TSHRGABRA1GABRB2POLBBCHE | |
| SCHEMBL15639790 | 0.82 | TSHR (0.64) | TSHRGABRA1GABRB2POLBBCHE | |
| SCHEMBL936321 | 0.82 | TSHR (0.63) | TSHRGABRA1GABRB2POLBBCHE | |
| SCHEMBL1238318 | 0.82 | TSHR (0.63) | TSHRGABRA1GABRB2POLBBCHE | |
| SCHEMBL4061536 | 0.81 | GABRA1 (0.59) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL11418774 | 0.81 | TSHR (0.57) | TSHRGABRA1GABRB2POLBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316170-B2 | COATING, EXPOSURE, DEVELOPMENT AND HEAT TREATMENT | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-11-13 | — | — | US | disclosed |