Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 5/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | PLG | P00747 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11298806 | 0.88 | PLAU (0.65) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL7879342 | 0.88 | PLAU (0.65) | PLAUPRSS1PLGF2F10 | |
| Hydrochloric Acid SCHEMBL11295243 | 0.87 | F2 (0.55) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL14599542 | 0.82 | PLAU (0.79) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL21017925 | 0.82 | PLAU (0.61) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL14355113 | 0.82 | PLAU (0.62) | PLAUPRSS1PLGF2F10 | |
| Hydrochloric Acid SCHEMBL11293360 | 0.81 | PLAU (0.64) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL23775598 | 0.81 | PLAU (0.48) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL5401865 | 0.81 | PLAU (0.56) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL5396848 | 0.81 | PLAU (0.60) | PLAUPRSS1PLGF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | PAM, AMPD1, AMPD3 | PLAU 699/4885PRSS1 652/4885PLG 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.