Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 15/20 | 0.40 |
| ▸ | PPARA | Q07869 | 12/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879351 | 1.00 | FFAR1 (0.40) | FFAR1PPARGPPARATARBP2KDM4E | |
| SCHEMBL9436318 | 0.83 | PPARG (0.43) | FFAR1PPARGPPARATARBP2KDM4E | |
| SCHEMBL7879344 | 0.70 | PPARG (0.46) | PPARGPPARATARBP2KDM4EPPARD | |
| SCHEMBL7877729 | 0.70 | PPARG (0.46) | PPARGPPARATARBP2KDM4EPPARD | |
| SCHEMBL4929594 | 0.70 | KDM4E (0.47) | PPARGPPARATARBP2KDM4ERAB9A | |
| SCHEMBL9008061 | 0.69 | KDM4E (0.41) | PPARGPPARATARBP2KDM4EPPARD | |
| SCHEMBL4918327 | 0.68 | TARBP2 (0.46) | PPARGPPARATARBP2KDM4ERAB9A | |
| SCHEMBL7737637 | 0.68 | KDM4E (0.46) | PPARGPPARATARBP2KDM4ERAB9A | |
| SCHEMBL17540833 | 0.68 | KDM4E (0.49) | PPARGPPARATARBP2KDM4ERAB9A | |
| SCHEMBL4263081 | 0.67 | NR1H4 (0.51) | TARBP2KDM4ERAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329408-B1 | HYPOCHOLESTEROLEMIC AGENTS; OPTICALLY PURE | PFIZER INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0641338-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONES AND INTERMEDIATES | PFIZER INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993002079-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONES AND INTERMEDIATES | PFIZER INC. (US) | 1993-02-04 | — | — | WO | disclosed |