Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 16/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.46 |
| ▸ | NEK2 | P51955 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7881625 | 0.91 | MTOR (0.52) | MTORPIK3CANEK2 | |
| SCHEMBL7880600 | 0.85 | MTOR (0.54) | MTOR | |
| SCHEMBL7876711 | 0.85 | MTOR (0.56) | MTORPIK3CA | |
| SCHEMBL7878557 | 0.84 | MTOR (0.74) | MTORPIK3CA | |
| SCHEMBL7879485 | 0.84 | MTOR (0.75) | MTORPIK3CA | |
| SCHEMBL6893409 | 0.84 | PIK3CA (0.56) | MTORPIK3CA | |
| SCHEMBL694993 | 0.83 | MTOR (0.75) | MTORPIK3CA | |
| SCHEMBL12773458 | 0.82 | MTOR (0.75) | MTORPIK3CA | |
| SCHEMBL12773450 | 0.81 | MTOR (0.76) | MTORPIK3CA | |
| SCHEMBL7873065 | 0.81 | MTOR (0.58) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122069-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |