Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7888778 | 0.98 | HTR2C (0.59) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL31690776 | 0.88 | HTR2C (0.58) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL7879540 | 0.83 | HTR2C (0.44) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A | |
| Hydrochloric Acid SCHEMBL4892816 | 0.82 | HTR2C (0.60) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A | |
| Hydrochloric Acid SCHEMBL4892806 | 0.82 | HTR2C (0.60) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A | |
| Hydrochloric Acid SCHEMBL7887340 | 0.82 | HTR2C (0.45) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A | |
| Hydrochloric Acid SCHEMBL4892811 | 0.82 | HTR2C (0.60) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL7887349 | 0.82 | HTR2C (0.58) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL10840665 | 0.81 | HTR2C (0.57) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL10840668 | 0.81 | HTR2C (0.57) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109786-A1 | PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014067-A1 | PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-03-16 | — | — | WO | disclosed |