Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7887340 | 0.98 | HTR2C (0.45) | HTR2CSLC6A4SLC6A2SLC6A3ALK | |
| SCHEMBL22580716 | 0.83 | HTR2C (0.41) | HTR2CALKHTR2BHTR2AHTR1A | |
| SCHEMBL7879557 | 0.83 | HTR2C (0.58) | HTR2CSLC6A4SLC6A2SLC6A3ALK | |
| Hydrochloric Acid SCHEMBL7888778 | 0.82 | HTR2C (0.59) | HTR2CSLC6A4SLC6A2SLC6A3ALK | |
| SCHEMBL12975930 | 0.79 | HTR2C (0.44) | HTR2CSLC6A2HTR2BHTR2AHTR1A | |
| SCHEMBL6042100 | 0.76 | PDE4B (0.52) | ALKHTR2A | |
| SCHEMBL22580687 | 0.76 | HTR2C (0.38) | HTR2CALKHTR2BHTR2AHTR1A | |
| SCHEMBL9458029 | 0.75 | HTR1A (0.44) | HTR2CHTR2BHTR2AHTR1A | |
| SCHEMBL7443635 | 0.75 | HTR2C (0.60) | HTR2CALKHTR2BHTR2AHTR6 | |
| SCHEMBL9458013 | 0.75 | HTR1A (0.44) | HTR2CHTR2BHTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1316994-A | Piperidine derivatives | HOFFMANN LA ROCHE (CH) | 2001-10-10 | — | — | CN | disclosed |
| EP-1109786-A1 | PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014067-A1 | PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-03-16 | — | — | WO | disclosed |