SCHEMBL7879592

SCHEMBL7879592

C=CC(=O)OCCC[SiH2]OC(CC)CC

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.54
HPGD P15428 1/20 0.54
ALDH1A1 P00352 4/20 0.50
CYP3A4 P08684 2/20 0.50
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
HSD17B10 Q99714 1/20 0.42
THRB P10828 2/20 0.40
ATM Q13315 1/20 0.37
HCAR2 Q8TDS4 3/20 0.33
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7880363 0.93 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL229761 0.86 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL1014595 0.84 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL7876341 0.83 ATM (0.43) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL2496766 0.83 TSHR (0.52) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL20555649 0.82 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL1803889 0.81 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL22115829 0.81 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL22115824 0.80 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL393550 0.79 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104203570-B Transparent overlay body and its manufacture method 马自达汽车株式会社 2017-08-25 CN disclosed
CN-105579123-A Inorganic particle dispersion liquid, inorganic particle-containing composition, coating film, plastic base with coating film, and display device SUMITOMO OSAKA CEMENT CO LTD 2016-05-11 CN disclosed
CN-105307753-A Organic el element JSR CORP 2016-02-03 CN disclosed
CN-102369225-B Curable composition and cured product thereof SHOWA DENKO KK 2015-06-24 CN disclosed
CN-104203570-A Transparent layered object and process for producing same MAZDA MOTOR 2014-12-10 CN disclosed
US-6331373-B1 CHARGE STABILITY AND FLUIDITY NIPPON SHOKUBAI CO., LTD. (JP) 2001-12-18 US disclosed