SCHEMBL1014595

SCHEMBL1014595

C=CC(=O)OCCC[SiH2]OC(C)C

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.53
ALDH1A1 P00352 4/20 0.53
CYP3A4 P08684 2/20 0.53
HPGD P15428 1/20 0.53
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 2/20 0.38
ATM Q13315 1/20 0.35
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HCAR2 Q8TDS4 3/20 0.32
TDP1 Q9NUW8 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2496766 0.89 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL229761 0.86 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL27541005 0.84 TSHR (0.47) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7879592 0.84 TSHR (0.54) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1803889 0.83 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7593092 0.82 ATM (0.42) TSHRALDH1A1CYP3A4HPGDATM
SCHEMBL7511201 0.82 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL20555649 0.81 TSHR (0.51) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL393550 0.81 TSHR (0.47) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL336349 0.81 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111466042-B Fluoropolymer membranes for electrochemical devices 索尔维公司 2024-03-29 CN claimed
CN-116903259-A Hybrid organic/inorganic composite materials based on fluoropolymers 索尔维特殊聚合物意大利有限公司 2023-10-20 CN claimed
CN-113261139-A Fluoropolymer hybrid composites 索尔维公司 2021-08-13 CN claimed
CN-112789065-A Medical device 微仙美国有限公司 2021-05-11 CN claimed
CN-111566062-A Fluoropolymer-based hybrid organic/inorganic composite materials 索尔维特殊聚合物意大利有限公司 2020-08-21 CN claimed
CN-111466042-A Fluoropolymer membranes for electrochemical devices 索尔维公司 2020-07-28 CN claimed
EP-1241190-B1 Rubber composite GOODYEAR TIRE & RUBBER (US) 2005-01-26 EP claimed
US-20030019554-A1 Rubber composite containing in situ formed filler reinforcement and article, such as a tire, having a component comprised thereof GOODYEAR TIRE & RUBBER COMPANY, THE 2003-01-30 US claimed
EP-1241190-A1 Rubber composite THE GOODYEAR TIRE & RUBBER COMPANY (US) 2002-09-18 EP claimed
US-4886852-A PREPARING NONAQUEOUS DISPERSION IN ORGANIC SOLVENT, THEN NEUTRALIZATION KANSAI PAINT COMPANY, LIMITED (JP) 1989-12-12 US claimed
CN-114402466-B Fluoropolymer hybrid composites SIENSCO (BE) 2026-05-26 CN disclosed
US-12509584-B2 Silicone rubber compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2025-12-30 US disclosed
US-12497518-B2 Resin-coated metal powder, method for producing same and aqueous coating composition using same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-12-16 US disclosed
CN-120202247-A Silane compound and composition containing same 昕特玛私人有限公司 2025-06-24 CN disclosed
CN-119502499-B High-barrier breathable PE packaging film and preparation process thereof 安徽紫金新材料科技股份有限公司 2025-04-25 CN disclosed
US-5872170-A HYDROSILYLATION CURABLE ELECTRICALLY CONDUCTIVE SILICONE ELASTOMER COMPOSITION CONTAINING AN ACRYLIC FUNCTIONAL GROUP-CONTAINING ORGANOPOLYSILOXANE DOWN CORNING TORAY SILICONE CO., LTD. (JP) 1999-02-16 US disclosed
EP-0803542-A2 Electrically conductive silicone elastomer compositions and use for manufacturing semiconductor devices Dow Corning Toray Silicone Company Ltd. (JP) 1997-10-29 EP disclosed
US-5538831-A Thermal transfer film DAI NIPPON PRINTING CO., LTD. (JP) 1996-07-23 US disclosed
EP-0668302-A1 Catalyst for reactive hot melt adhesives National Starch and Chemical Investment Holding Corporation (US) 1995-08-23 EP disclosed
US-4886852-A PREPARING NONAQUEOUS DISPERSION IN ORGANIC SOLVENT, THEN NEUTRALIZATION KANSAI PAINT COMPANY, LIMITED (JP) 1989-12-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509584-B2 Silicone rubber compositions SMC3, SMC2, SRRM2 TSHR 1473/4885ALDH1A1 3216/4885CYP3A4 4640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.