Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.40 |
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184609 | 0.98 | CES2 (0.42) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL16594597 | 0.92 | CA1 (0.39) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL10399823 | 0.88 | FFAR4 (0.45) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL10950789 | 0.88 | FFAR4 (0.45) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL11864750 | 0.88 | FFAR4 (0.45) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL8110729 | 0.88 | FFAR4 (0.45) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL11359540 | 0.88 | FFAR4 (0.45) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL9451147 | 0.88 | FFAR4 (0.45) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL21271848 | 0.88 | FFAR4 (0.45) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL8181135 | 0.87 | CA1 (0.37) | CES2CES1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331627-B1 | Intermediates of benzoxazinone derivatives and preparation thereof | REDDY'S LABORATORIES LTD. (IN) | 2001-12-18 | — | — | US | disclosed |