Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28682288 | 0.79 | LMNA (0.37) | LMNAKMT2ADGAT1CA12CA14 | |
| SCHEMBL28478206 | 0.75 | KMT2A (0.40) | LMNAKMT2ADGAT1CA12CA14 | |
| SCHEMBL869806 | 0.75 | LMNA (0.40) | LMNAKMT2ADGAT1CA12CA14 | |
| SCHEMBL4249210 | 0.75 | KMT2A (0.40) | LMNAKMT2ADGAT1CA12CA14 | |
| SCHEMBL17094539 | 0.73 | LMNA (0.39) | LMNAKMT2ADGAT1CA12CA14 | |
| SCHEMBL6882473 | 0.73 | SMN1; SMN2 (0.40) | KMT2ACA12CA14 | |
| SCHEMBL7381837 | 0.73 | KMT2A (0.39) | LMNAKMT2ADGAT1CA12CA14 | |
| SCHEMBL3183015 | 0.73 | LMNA (0.39) | LMNAKMT2ADGAT1CA12CA14 | |
| SCHEMBL17094267 | 0.73 | LMNA (0.39) | LMNAKMT2ADGAT1CA12CA14 | |
| SCHEMBL79871 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055082-A2 | INTERMEDIATES FOR BIOLOGICALLY ACTIVE COMPOUNDS | ROHM AND HAAS COMPANY (US) | 2001-08-02 | — | — | WO | disclosed |