Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL3255325 | 0.98 | RECQL (0.44) | RECQLTSHRGLAHPGDMAPK1 | |
| Tetrabuthylammonium SCHEMBL11225223 | 0.80 | RECQL (0.53) | RECQLTSHRGLAHPGDMAPK1 | |
| Tetrabuthylammonium SCHEMBL1259012 | 0.79 | SLC22A1 (0.55) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL2937219 | 0.77 | RECQL (0.32) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL2769491 | 0.77 | RECQL (0.32) | RECQLTSHRGLAHPGDMAPK1 | |
| Tetrabuthylammonium SCHEMBL2287273 | 0.77 | RECQL (0.78) | RECQLTSHRGLAHPGDMAPK1 | |
| Tetrabuthylammonium SCHEMBL991019 | 0.75 | SLC22A1 (0.55) | RECQLTSHRGLAHPGDMAPK1 | |
| Tetrabuthylammonium SCHEMBL10840728 | 0.75 | SLC22A1 (0.55) | RECQLTSHRGLAHPGDMAPK1 | |
| Tetrabuthylammonium SCHEMBL5574939 | 0.75 | SLC22A1 (0.55) | RECQLTSHRGLAHPGDMAPK1 | |
| Tetrabuthylammonium SCHEMBL243898 | 0.74 | SLC22A1 (0.67) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333176-B1 | ENZYMATIC CLEAVAGE OF C-TERMINAL AMINO GROUP FROM PEPTIDE AMIDE, DEAMINATION WITH PEPTIDE AMIDASE, INCUBATION AND INOCULATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 2001-12-25 | — | — | US | disclosed |
| US-5985632-A | Peptide amidase from xanthomonas | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1999-11-16 | — | — | US | disclosed |