Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 18/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.52 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872340 | 0.88 | MTOR (0.55) | MTORCCNE1CDK2GSK3APIK3CA | |
| SCHEMBL7875765 | 0.88 | MTOR (0.56) | MTORCCNE1CDK2PIK3CA | |
| SCHEMBL7883941 | 0.87 | MTOR (0.50) | MTORCCNE1CDK2PIK3CA | |
| SCHEMBL12773632 | 0.85 | MTOR (0.71) | MTORCCNE1CDK2GSK3APIK3CA | |
| SCHEMBL12137706 | 0.84 | MTOR (0.46) | MTORCCNE1CDK2PIK3CANPC1 | |
| SCHEMBL694987 | 0.83 | MTOR (0.77) | MTORCCNE1CDK2GSK3APIK3CA | |
| SCHEMBL6893242 | 0.83 | PIK3CA (0.56) | MTORPIK3CA | |
| SCHEMBL7871050 | 0.82 | MTOR (0.47) | MTOR | |
| SCHEMBL12773417 | 0.81 | MTOR (0.73) | MTORCCNE1CDK2GSK3APIK3CA | |
| SCHEMBL12773419 | 0.80 | MTOR (0.73) | MTORCCNE1CDK2GSK3APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122069-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |