Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 8/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877513 | 0.86 | GABRP (0.51) | MTORMKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL12773638 | 0.82 | MTOR (0.67) | MTORMKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL7880673 | 0.82 | MTOR (0.52) | MTOR | |
| SCHEMBL7883941 | 0.82 | MTOR (0.50) | MTORALOX5APFEN1 | |
| SCHEMBL12138107 | 0.81 | MKNK1 (0.43) | MTORALOX5APFEN1MKNK1MKNK2 | |
| SCHEMBL5543060 | 0.81 | MKNK1 (0.65) | ALOX5APFEN1MKNK1MKNK2KDM4E | |
| SCHEMBL695584 | 0.81 | MTOR (0.74) | MTOR | |
| SCHEMBL6894184 | 0.80 | PIK3CA (0.48) | MTORALOX5APFEN1MKNK1MKNK2 | |
| SCHEMBL12773444 | 0.78 | MTOR (0.69) | MTOR | |
| SCHEMBL12773423 | 0.77 | MTOR (0.71) | MTORMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122069-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |