Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7884598 | 0.92 | GYS1 (0.37) | MAOBCFDF2MEN1KMT2A | |
| SCHEMBL7877987 | 0.92 | MRGPRX4 (0.36) | MAOBCFDF2MEN1KMT2A | |
| SCHEMBL7873532 | 0.92 | MAP2 (0.38) | MAOBF2MEN1KMT2ARXFP1 | |
| Hydrochloric Acid SCHEMBL7873286 | 0.91 | MAP2 (0.37) | MAOBF2NOS1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7881035 | 0.89 | MAOB (0.36) | MAOBCFDF2MEN1KMT2A | |
| SCHEMBL7881478 | 0.88 | PPARG (0.40) | PARP1F2MEN1KMT2ARXFP1 | |
| SCHEMBL7881416 | 0.87 | MAOB (0.36) | MAOBF2ALOX5 | |
| SCHEMBL7881394 | 0.87 | MAOB (0.37) | MAOBCFDMGMTF2NOS1 | |
| SCHEMBL7873843 | 0.86 | RHEB (0.34) | MAOBF2MEN1KMT2ARXFP1 | |
| Hydrochloric Acid SCHEMBL7879399 | 0.86 | MAOB (0.37) | MAOBF2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248772-B1 | HYPOTENSIVE AGENTS; ANTIARRHYTHMIA AGENTS; ANTIDIABETIC AGENTS; ANTIPROLIFERATIVE AGENTS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| US-6169107-B1 | USEFUL FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY INCREASED SODIUM/PROTON (NA.SUP.+ /H.SUP.+) EXCHANGER ACTIVITY, FOR EXAMPLE, HYPERTENSION, ARRHYTHMIA, ANGINA PECTORIS, CARDIAC HYPERTROPHY, DIABETES MELLITUS | SUMITOMO PHARMACEUTICAL CO., LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| EP-0708091-A2 | Indoloylguanidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |