Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | MYOC | Q99972 | 1/20 | 0.66 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.66 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177730 | 0.89 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL6302157 | 0.89 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL8651307 | 0.89 | MEN1 (0.79) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL7881346 | 0.88 | KMT2A (0.79) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL6855014 | 0.88 | KMT2A (0.79) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL7696438 | 0.88 | KMT2A (0.79) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL11055960 | 0.86 | MEN1 (0.85) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL5465076 | 0.86 | TDP1 (0.78) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL14877369 | 0.85 | CES1 (0.75) | MEN1KMT2ANPC1MAPTMAPK1 | |
| 4-Nitrobenzoic Acid SCHEMBL43476 | 0.85 | TDP1 (1.00) | MEN1KMT2AMAPK1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187285-B1 | IN PARTICULAR MAGNETIC RESONANCE IMAGING (MRI) FOR MAGNETIC CATIONS. | GUERBET (FR) | 2001-02-13 | — | — | US | disclosed |