Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.85 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | MITF | O75030 | 1/20 | 0.70 |
| ▸ | MYOC | Q99972 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.68 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | DDX3X | O00571 | 1/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylurea SCHEMBL27302793 | 0.98 | MEN1 (0.81) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL23069044 | 0.93 | MEN1 (0.73) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL1177730 | 0.92 | MEN1 (1.00) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL6302157 | 0.92 | MEN1 (1.00) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11832409 | 0.91 | MEN1 (0.88) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL14877369 | 0.89 | CES1 (0.75) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11027238 | 0.87 | MEN1 (0.88) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL6302417 | 0.87 | MEN1 (0.89) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL7881307 | 0.86 | MEN1 (1.00) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL6297231 | 0.85 | MAPT (0.84) | MEN1KMT2AMAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794408-B | Pyrimidine phenylurea anti-tumor compound and preparation method and application thereof | 中国医科大学 | 2020-04-21 | — | — | CN | claimed |
| CN-117800925-A | Phenyl ureido quinazoline compound, preparation method thereof and application thereof in preparation of medicines for preventing or treating liver cancer | 浙江工业大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-117486809-A | 2-chloroquinazoline compound, preparation method and application thereof in preparation of medicines for preventing or treating breast cancer | 浙江工业大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-114794141-B | Compound weeding composition and compound herbicide | 浙江新安化工集团股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-108794408-B | Pyrimidine phenylurea anti-tumor compound and preparation method and application thereof | 中国医科大学 | 2020-04-21 | — | — | CN | disclosed |
| EP-3524656-A1 | NOVEL HYDROGELATOR | National University Corporation Shizuoka University (JP) | 2019-08-14 | — | — | EP | disclosed |
| US-20190241598-A1 | NOVEL HYDROGELATOR | NATIONAL UNIVERSITY CORPORATION SHIZUOKA UNIVERSITY (JP) | 2019-08-08 | — | — | US | disclosed |
| CN-106699755-B | A kind of aza-acridine class compound and preparation method thereof and purposes | 清华大学深圳研究生院 | 2018-09-21 | — | — | CN | disclosed |
| CN-106699755-A | Aza-acridine compound and preparation method and application thereof | 清华大学深圳研究生院 | 2017-05-24 | — | — | CN | disclosed |
| CN-104650111-A | Aryl urea and aryl amide substituted oxaole pyrimindine compounds as well as preparation method and application thereof | UNIV CHINA PHARMA | 2015-05-27 | — | — | CN | disclosed |
| CN-102532103-B | Quinazolinyl aryl urea derivatives and preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2014-07-09 | — | — | CN | disclosed |
| CN-102532103-A | Quinazolinyl aryl urea derivatives and preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2012-07-04 | — | — | CN | disclosed |
| US-4444863-A | UREA COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241598-A1 | NOVEL HYDROGELATOR | AGL, GCK, CCNL2 | MEN1 3201/4885KMT2A 2810/4885MAPT 4373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.